Fri Jul 01 2022

59 articles - From Friday Jun 24 2022 to Friday Jul 01 2022

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Guidelines

Guidelines, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews


Original articles

RCT, clinical trials, retrospective studies, etc…

Ann Intern Med

Life Expectancy for White, Black, and Hispanic Race/Ethnicity in U.S. States: Trends and Disparities, 1990 to 2019.

Disparity in LE across states was greater when race/ethnicity groups were considered. Disparities across al state-race/ethnicity groups in general have decreased over the past 3 decades. Within each race/ethnicity group, disparities across states have increased. Although racial/ethnic disparities decreased in most of the 23 states for which LE was estimated for al 3 groups, they increased for females in 7 states and males in 5 states. Primary funding source National Heart, Lung, and Blood Institute.

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Strengthening Food and Nutrition Security to Promote Public Health in the United States: A Position Paper From the American College of Physicians.

Governments and payers must support these efforts by providing sufficient resources to practices to fulfill this role. In this position paper, the American College of Physicians (ACP) offers several policy recommendations to strengthen the federal food-insecurity response and empower physicians and other medical professionals to better address those social drivers of health occurring beyond the office doors.

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The Underuse of Medicare's Prevention and Coordination Codes in Primary Care : A Cross-Sectional and Modeling Study.

Primary care physicians forego considerable amounts of revenue because they infrequently use billing codes for prevention and coordination services despite having eligible patients and providing code-appropriate services to some of those patients. Therefore, creating additional billing codes for distinct activities in the MPFS may not be an effective strategy for supporting primary care. Primary funding source National Institute on Aging.

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Lancet

Early food intervention and skin emollients to prevent food allergy in young children (PreventADALL): a factorial, multicentre, cluster-randomised trial.

Our results support that early introduction of common allergenic foods is a safe and effective strategy to prevent food allergy. Funding Full funding sources listed at end of paper (see Acknowledgments).

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N Engl J Med

BNT162b2 Vaccine Effectiveness against Omicron in Children 5 to 11 Years of Age.

Our findings suggest that as omicron was becoming the dominant variant, two doses of the BNT162b2 messenger RNA vaccine provided moderate protection against documented SARS-CoV-2 infection and symptomatic Covid-19 in children 5 to 11 years of age. (Funded by the European Union through the VERDI project and others.).

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Fazirsiran for Liver Disease Associated with Alpha1-Antitrypsin Deficiency.

In this small trial, fazirsiran was associated with a strong reduction of Z-AAT concentrations in the serum and liver and concurrent improvements in liver enzyme concentrations. (Funded by Arrowhead Pharmaceuticals; AROAAT-2002 ClinicalTrials.gov number, NCT03946449.).

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Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma.

Intratumoral infusion of oncolytic virus DNX-2401 followed by radiotherapy in pediatric patients with DIPG resulted in changes in T-cell activity and a reduction in or stabilization of tumor size in some patients but was associated with adverse events. (Funded by the European Research Council under the European Union's Horizon 2020 Research and Innovation Program and others; EudraCT number, 2016-001577-33; ClinicalTrials.gov number, NCT03178032.).

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Ann Intern Med

Small Solutions for Primary Care Are Part of a Larger Problem.

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Urgent Call to Action: Engaging Hospitalists in Family Planning.

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Lancet

Cancer care: widening the scope of innovation.

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Offline: The UK, a knave among nations.

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N Engl J Med

Audio Interview: How Effective is Covid-19 Vaccination in Children?

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Lawmakers v. The Scientific Realities of Human Reproduction.

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Mantle-Cell Lymphoma.

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The Vaccine-Hesitant Moment.

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Virotherapy for Brain Tumors - Defining the Path to Success.

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Letters&Replies

Letters to the editors and authors’ replies

Lancet

Global burden of antimicrobial resistance: essential pieces of a global puzzle - Authors' reply.

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Global burden of antimicrobial resistance: essential pieces of a global puzzle.

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Global burden of antimicrobial resistance: essential pieces of a global puzzle.

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Global burden of antimicrobial resistance: essential pieces of a global puzzle.

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Global burden of antimicrobial resistance: essential pieces of a global puzzle.

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Global burden of antimicrobial resistance: essential pieces of a global puzzle.

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Guidelines for pregnant individuals with monkeypox virus exposure.

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N Engl J Med

Cancer-Associated Hypercalcemia.

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Cancer-Associated Hypercalcemia. Reply.

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Detection of Marburg Virus Disease in Guinea.

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Duration of Shedding of Culturable Virus in SARS-CoV-2 Omicron (BA.1) Infection.

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Fourth Dose of BNT162b2 mRNA Covid-19 Vaccine.

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Fourth Dose of BNT162b2 mRNA Covid-19 Vaccine. Reply.

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Immunogenicity and Safety of Beta-Adjuvanted Recombinant Booster Vaccine.

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Ivosidenib and Azacitidine in IDH1-Mutated AML.

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Ivosidenib and Azacitidine in IDH1-Mutated AML.

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Ivosidenib and Azacitidine in IDH1-Mutated AML. Reply.

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Mitapivat versus Placebo for Pyruvate Kinase Deficiency.

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Mitapivat versus Placebo for Pyruvate Kinase Deficiency. Reply.

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Nonoperative Management of Childhood Calvarial Langerhans-Cell Histiocytosis.

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Rilzabrutinib in Immune Thrombocytopenia.

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Rilzabrutinib in Immune Thrombocytopenia. Reply.

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SARS-CoV-2 Infection in Patients with a History of VITT.

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Others

all remaining publications eg case reports, images of the month, etc…

Ann Intern Med

Annals Graphic Medicine - Dr. Mom: A Letter to My Intern Self.

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Mapping the Color Line: Racial/Ethnic and Gender Disparities in Life Expectancy Across the United States.

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Medicare Codes for Primary Care: Expansions With Limitations.

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Who Was She?

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Lancet

Continuous glucose monitoring device causes consternation on chest x-ray.

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COVID-19 in North Korea.

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Early introduction of allergenic food for all infants.

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From drug prohibition to regulation: a public health imperative.

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Naomi Oreskes: understanding the denial of science.

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Nominees to lead PAHO announced.

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Sharpening the focus on powerful health stories: Highlights 2022 photography competition open for submissions.

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The 2022 Wakley Prize: compassion and connection.

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The UK benefits from a truly National Health Service.

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N Engl J Med

Case 20-2022: A 25-Year-Old Man with Vision Changes.

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Chalk-Stick Fracture.

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Cherry-Red Spot in Tay-Sachs Disease.

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Russia's War in Ukraine - The Devastation of Health and Human Rights.

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The Potency of a KRAS Silent Variant.

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The Solution Shop and the Production Line - The Case for a Frameshift for Physician Practices.

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Without Question.

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